CHEM 2425 Alpha Carbon Chemistry: Enols and Enolates Video Tutorials

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Enols, Enolates, and Alpha Substitution

Acidity of the Alpha Hydrogen

https://youtu.be/F670x2rtHqk Links to an external site.

 

Kinetic vs. Thermodynamic Enolate Formation

https://youtu.be/sBuM8hTGlag Links to an external site.

 

General Mechanism of Alpha Substitution

https://youtu.be/Qs2GAK_2Y3M Links to an external site.

 

Alpha Halogenation

https://youtu.be/537ZcOwKiXI Links to an external site.

 

The Haloform Reaction

https://youtu.be/wMyLAaJ1UIw Links to an external site.

 

The HVZ (Hell-Vollhard-Zelinsky) Reaction

https://youtu.be/HjyuvlEjY3U Links to an external site.

 

Alpha Alkylation

https://youtu.be/jVgAZAkaEV0 Links to an external site.

 

Stork Enamine Synthesis

https://youtu.be/YAM_LEHGHFQ Links to an external site.

 

 

 

Aldol and Claisen Reactions

Introduction to Aldol Addition and Condensation

https://youtu.be/OPwpzzgpF0s Links to an external site.

 

Aldol Addition/Condensation Mechanism

https://youtu.be/BTYN9AkPwE4 Links to an external site.

 

Mixed Aldol Condensation Reactions

https://youtu.be/FFOXo1HNxm0 Links to an external site.

 

Intramolecular Aldol Condensation Reactions

https://youtu.be/voE5Su9Xz3w Links to an external site.

 

The Claisen Condensation Reaction

https://youtu.be/hQKbf3SR-kc Links to an external site.

 

Dieckmann Condensation (Intramolecular Claisen Condensation)

https://youtu.be/TCx-Ra7VD2U Links to an external site.

 

 

 

Synthetic Application of Aldol and Claisen Reactions

Analyzing Claisen and Dieckmann Products for Synthesis

https://youtu.be/bGCkKkxqDy8 Links to an external site.

 

Beta Decarboxylation

https://youtu.be/e_8uZBNmY-4 Links to an external site.

 

The Malonic Ester Synthesis (of Carboxylic Acids)

https://youtu.be/MYWoKhm91HA Links to an external site.

 

The Acetoacetic Ester Synthesis (of Methyl Ketones)

https://youtu.be/hxyvNcTNH54 Links to an external site.

 

The Michael Reaction (1,4 Addition to a,B-Unsaturated Carbonyl)

https://youtu.be/CE0xEtRzQYM Links to an external site.

 

Robinson Annulation-An Introduction

https://youtu.be/pYfNB73Chq8 Links to an external site.

 

Robinson Annulation-Complete Mechanism and Examples

https://youtu.be/_wio-EENoW0 Links to an external site.

 

Stork Enamine Synthesis (Note: Use with Michael Reaction)

https://youtu.be/YAM_LEHGHFQ Links to an external site.